Nanotechnology to map and catalog with identification number the parts of human tissues as machines

November 16, 2021 0 Comments

How can a bean stem tell us so much about human tissue engineering? It was for this reason that the research began, taking an alternative path beyond DNA, and to verify this, an independent researcher published a study on, when studying iPSCs and other pluripotent plant cells, he decided to cut a bean stem completely from its roots. to the leaves. , using a tissue cutter, shortly after photocopying the cut parts to digitally reassemble and map the internal microfluidics as a template to be applied to artificial tissues. The study, called “Biomimetic and functional artificial tissues: mastering irrigation, nutrition, microfluids and nerve networks to keep cells alive”, exposes research on the life support of nerve cells that make up artificial tissues and organs .

Through a simple stalk of beans you can study the essence of life in its heart, providing relevant information to modern medicine and even for a possible understanding of the possibility of artificial life.

This research aims at collaborative work focused on the nutrition of cells in artificial tissues, in the long work of mapping the tissues and standardizing the parts, in addition to identifying with code the elements of the tissues and processes, for each circulatory and nervous system. The study also shows the potential that new sciences and technologies confer on the viability of new studies into artificial life, which is related to greater precision in understanding everything at the nanotopographic level, including the processes of biological tissues. Among the topics and ideas involved in the study, in addition to the future perspectives of this research, the following are contemplated:

• Cataloging of vessels and microfluidic parts and minimal process data to keep cells alive in tissues.

• Mapping and coding of each circulation microchannel with the identification number of the code linked to a data sheet.

• Generate information and precise data to feed new machines for the production of human artificial tissues.

• Generate cataloged information on biological spare parts with data sheets with complete specification and characterization

• Use traditional techniques of complex machine engineering and integrated circuit architecture for microfluidic networks in human tissues.

The future intention is to map all the microfluidic and bioelectric flora of human tissues and add an identification number to each irrigation circuit as spare parts, similar to engineering done in integrated circuit architecture or mechanics. Each line of circulation or communication flow is identified by calling its technical sheet with all the descriptive, technical and characterization specification to map the cellular structures in artificial tissues, their connections, work and the process they carry out to stay alive. With this, we will have a better understanding of the connections, receptors and their endings of nutrition, communication and fluid transport in a detailed nanotopography.

The idea is to map nanotopography to the surface of biological tissues at the level of cellular structure, including their connections, matrix of fluid and nerve networks. The generation of biological spare parts for use in artificial organs is a trend that is based on nanotechnology, in particular nanotopography, which will broaden our vision and reach the connections and supports to keep cells away from living tissues, giving a focus clearer to the details of each cell.

Nanotechnology and the techniques used in traditional engineering to map the components of the human body and document the parts with an identification number to call a datasheet presents enormous potential to gather and present the understanding of various specialties in a single descriptive manual . A technique similar to that performed in mechanical engineering used in the aircraft, helicopter, vehicle and complex machinery industries to have a history, control and knowledge of all the parts that make up the whole.

The main difficulty is not in the generation of new tissues, with techniques, for example, that use pluripotent stem cells induced by iPSC, but in the organization and functionalization of the tissues. When repairing two living cells of a tissue, the problem is to reconnect them, in a perfect regeneration, keeping intact the nutritional, electrical and structural communication network, in addition to making this connection recognized by the body. At this frontier of science and technology, we can clearly see the differences in the practical applications of biosciences and the limited scope of the new sciences.

However, nanotopography and engineering techniques alone may not be sufficient, for an entirely new tissue mapping technology, due to the complexity involved. The difference surrounding nanotechnology and bioscience is defined not only by measurements, but also by effects, events, methods, and processes.

Nanotechnology works in the range of 1-100 nm, biology and biosciences go far beyond dimensions, going from μm, nm, particle fragments around angstroms and moles. In the case of biosciences, this anthropometry of biological components does not have a standard, but we have some known approximations, biomolecules are between 2-16nm, human cells are at 25-100μm, in addition to measurements of some viruses close to 150nm , the parts of the body are very varied. In this new biological anthropometry involving micro / nanoparticles, the necessary parts of tissues and parasites must be considered. In general, in addition to the measurements, the whole set is needed, as in process engineering, it is the knowledge and precise uses, effects, events, processes and energies involved. Research as simple but deep as there are many cases in India especially that are exemplary and that are true seeds of great achievements, origin of great innovations that began in the workshops, and with the accumulation of knowledge in innovation comes the great advance, and the new technologies take shape.

As presented in the recently published study titled “Biomimetic and Functional Artificial Tissues: Mastering Irrigation, Nutrition, Microfluidics, and Nerve Networks to Keep Cells Alive.” There are future prospects with a precise code for the identification of biological circuits in all channels of fluid and nutrition circulation, more precise studies and even standardizations will be feasible. With these studies, the viability of artificial organs will be more and more precise, and even new formats of organs may become common, as has already been done in spare parts for machines. In addition to identifying damaged tissues that require regeneration with an understanding and a number at each termination, this preliminary study brings more technique as engineering standardization to this science.

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